| P | Pts | GF | GA | GD | w | d | l | ||
|---|---|---|---|---|---|---|---|---|---|
| 1. | Philadelphia Union | 25 | 50 | 43 | 24 | 19 | 15 | 5 | 5 |
| 2. | Cincinnati FC | 25 | 49 | 39 | 31 | 8 | 15 | 4 | 6 |
| 3. | Nashville SC | 25 | 47 | 42 | 26 | 16 | 14 | 5 | 6 |
| 4. | San Diego FC | 25 | 46 | 48 | 32 | 16 | 14 | 4 | 7 |
| 5. | Vancouver Whitecaps | 24 | 45 | 42 | 26 | 16 | 13 | 6 | 5 |
| 6. | Minnesota United FC | 25 | 44 | 42 | 28 | 14 | 12 | 8 | 5 |
| 7. | Columbus Crew | 25 | 44 | 41 | 36 | 5 | 12 | 8 | 5 |
| 8. | Inter Miami CF | 22 | 42 | 49 | 34 | 15 | 12 | 6 | 4 |
| 9. | Orlando City | 25 | 41 | 46 | 33 | 13 | 11 | 8 | 6 |
| 10. | New York City FC | 24 | 38 | 34 | 29 | 5 | 11 | 5 | 8 |
| 11. | Charlotte FC | 25 | 38 | 43 | 39 | 4 | 12 | 2 | 11 |
| 12. | Seattle Sounders | 24 | 38 | 39 | 35 | 4 | 10 | 8 | 6 |
| 13. | Portland Timbers | 24 | 37 | 33 | 32 | 1 | 10 | 7 | 7 |
| 14. | Los Angeles FC | 22 | 36 | 39 | 28 | 11 | 10 | 6 | 6 |
| 15. | Chicago Fire | 24 | 35 | 45 | 40 | 5 | 10 | 5 | 9 |
| 16. | New York Red Bulls | 25 | 33 | 39 | 36 | 3 | 9 | 6 | 10 |
| 17. | Austin FC | 23 | 33 | 21 | 26 | -5 | 9 | 6 | 8 |
| 18. | Real Salt Lake | 24 | 31 | 26 | 30 | -4 | 9 | 4 | 11 |
| 19. | Colorado Rapids | 25 | 30 | 31 | 39 | -8 | 8 | 6 | 11 |
| 20. | San Jose Earthquakes | 25 | 29 | 47 | 44 | 3 | 7 | 8 | 10 |
| 21. | Houston Dynamo | 24 | 27 | 30 | 39 | -9 | 7 | 6 | 11 |
| 22. | New England Revolution | 24 | 25 | 31 | 35 | -4 | 6 | 7 | 11 |
| 23. | FC Dallas | 24 | 25 | 35 | 45 | -10 | 6 | 7 | 11 |
| 24. | Sporting Kansas City | 24 | 24 | 36 | 45 | -9 | 6 | 6 | 12 |
| 25. | Toronto FC | 24 | 21 | 25 | 32 | -7 | 5 | 6 | 13 |
| 26. | Atlanta United FC | 24 | 21 | 29 | 45 | -16 | 4 | 9 | 11 |
| 27. | D.C. United | 25 | 19 | 22 | 49 | -27 | 4 | 7 | 14 |
| 28. | St. Louis City SC | 24 | 18 | 24 | 40 | -16 | 4 | 6 | 14 |
| 29. | CF Montreal | 25 | 18 | 23 | 46 | -23 | 4 | 6 | 15 |
| 30. | Los Angeles Galaxy | 24 | 16 | 28 | 48 | -20 | 3 | 7 | 14 |