| P | Pts | GF | GA | GD | w | d | l | ||
|---|---|---|---|---|---|---|---|---|---|
| 1. | Philadelphia Union | 18 | 37 | 34 | 19 | 15 | 11 | 4 | 3 |
| 2. | Vancouver Whitecaps | 17 | 35 | 31 | 14 | 17 | 10 | 5 | 2 |
| 3. | San Diego FC | 18 | 33 | 33 | 20 | 13 | 10 | 3 | 5 |
| 4. | Cincinnati FC | 18 | 33 | 26 | 24 | 2 | 10 | 3 | 5 |
| 5. | Nashville SC | 18 | 32 | 32 | 21 | 11 | 9 | 5 | 4 |
| 6. | Columbus Crew | 18 | 31 | 29 | 25 | 4 | 8 | 7 | 3 |
| 7. | Orlando City | 18 | 30 | 32 | 22 | 10 | 8 | 6 | 4 |
| 8. | Minnesota United FC | 18 | 30 | 28 | 20 | 8 | 8 | 6 | 4 |
| 9. | Portland Timbers | 18 | 30 | 28 | 24 | 4 | 8 | 6 | 4 |
| 10. | Inter Miami CF | 16 | 29 | 36 | 27 | 9 | 8 | 5 | 3 |
| 11. | New York City FC | 18 | 28 | 24 | 20 | 4 | 8 | 4 | 6 |
| 12. | New York Red Bulls | 18 | 27 | 29 | 21 | 8 | 8 | 3 | 7 |
| 13. | Los Angeles FC | 16 | 26 | 30 | 23 | 7 | 7 | 5 | 4 |
| 14. | Seattle Sounders | 18 | 26 | 25 | 25 | 0 | 7 | 5 | 6 |
| 15. | Austin FC | 19 | 26 | 15 | 21 | -6 | 7 | 5 | 7 |
| 16. | Chicago Fire | 17 | 25 | 35 | 31 | 4 | 7 | 4 | 6 |
| 17. | Charlotte FC | 18 | 25 | 29 | 29 | 0 | 8 | 1 | 9 |
| 18. | San Jose Earthquakes | 18 | 23 | 35 | 29 | 6 | 6 | 5 | 7 |
| 19. | New England Revolution | 16 | 23 | 19 | 15 | 4 | 6 | 5 | 5 |
| 20. | Colorado Rapids | 18 | 22 | 18 | 25 | -7 | 6 | 4 | 8 |
| 21. | FC Dallas | 17 | 21 | 22 | 28 | -6 | 5 | 6 | 6 |
| 22. | Houston Dynamo | 18 | 20 | 23 | 28 | -5 | 5 | 5 | 8 |
| 23. | Real Salt Lake | 18 | 18 | 18 | 25 | -7 | 5 | 3 | 10 |
| 24. | D.C. United | 19 | 18 | 17 | 38 | -21 | 4 | 6 | 9 |
| 25. | Atlanta United FC | 18 | 17 | 21 | 34 | -13 | 4 | 5 | 9 |
| 26. | Sporting Kansas City | 18 | 16 | 28 | 35 | -7 | 4 | 4 | 10 |
| 27. | St. Louis City SC | 18 | 15 | 17 | 26 | -9 | 3 | 6 | 9 |
| 28. | Toronto FC | 17 | 13 | 18 | 24 | -6 | 3 | 4 | 10 |
| 29. | CF Montreal | 18 | 11 | 15 | 33 | -18 | 2 | 5 | 11 |
| 30. | Los Angeles Galaxy | 18 | 8 | 18 | 39 | -21 | 1 | 5 | 12 |